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How exactly does bypass change your fat metabolism?



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I know this question gets a little deeper on the physiology of things, but if someone out there can explain this, that'd be awesome. Please get as technical as you'd like :)

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1 hour ago, Kimmie K said:

I know this question gets a little deeper on the physiology of things, but if someone out there can explain this, that'd be awesome. Please get as technical as you'd like :)

That's a great question...Me personally...do not believe that it changes after surgery or I've read on this forum that some say the surgery resets the metabolism?? My Doctor nor any one from his team never mentioned that to me...my metabolism was shot before surgery because of a thyroid condition and after surgery I am still on thyroid meds and I still lose weight slow and have to work my butt off to lose every ounce.

Don't get me wrong, I am very pleased with my weight loss results and feel that I am losing at a steady rate for me. I did not go into this surgery thinking that when I wake up from surgery a miracle was going to happen, I knew it would be a tool to help me not eat such large portions any longer and it really is doing it's part and I am doing the rest by exercising and making healthy food choices, low fat, low carb. etc...I know my body, and this is the plan that works for me.

I would love to read some statistics that states that these type of surgeries changes our metabolism because it sure did not change mine, therefore I think I should be entitled to a partial refund 😉

✌️Just my thought @Kimmie K

Edited by Wanda247

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13 minutes ago, Wanda247 said:

That's a great question...Me personally...do not believe that it changes after surgery or I've read on this forum that some say the surgery resets the metabolism?? My Doctor nor any one from his team never mentioned that to me...my metabolism was shot before surgery because of a thyroid condition and after surgery I am still on thyroid meds and I still lose weight slow and have to work my butt off to lose every ounce.

Don't get me wrong, I am very pleased with my weight loss results and feel that I am losing at a steady rate for me. I did not go into this surgery thinking that when I wake up from surgery a miracle was going to happen, I knew it would be a tool to help me not eat such large portions any longer and it really is doing it's part and I am doing the rest by exercising and making healthy food choices, low fat, low carb. etc...I know my body, and this is the plan that works for me.

I would love to read some statistics that states that these type of surgeries changes our metabolism because it sure did not change mine, therefore I think I should be entitled to a partial refund 😉

✌️Just my thought @Kimmie K

Right, I haven't seen this topic addressed in the forums which is why I bring it up. I'm very surprised it has not been talked about. I read A LOT...here's a website I read this morning that sparked my question. It's kind of high level and doesn't get too deep, but it talks about a change in genetic expression in bypass patients, specifically in markers of 2 genes that control glucose and fat metabolism, PGC-1 alpha and PDK4. Extremely interesting, short read that I'll be looking into deeper before I see my surgeon for the 1st time in a couple weeks. Check it out! http://www.thedoctorwillseeyounow.com/content/diabetes/art4005.html

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6 minutes ago, Kimmie K said:

Right, I haven't seen this topic addressed in the forums which is why I bring it up. I'm very surprised it has not been talked about. I read A LOT...here's a website I read this morning that sparked my question. It's kind of high level and doesn't get too deep, but it talks about a change in genetic expression in bypass patients, specifically in markers of 2 genes that control glucose and fat metabolism, PGC-1 alpha and PDK4. Extremely interesting, short read that I'll be looking into deeper before I see my surgeon for the 1st time in a couple weeks. Check it out! http://www.thedoctorwillseeyounow.com/content/diabetes/art4005.html

Thanks for sharing that and yes it didn't go into a lot of detail but it's true about diabetes and high blood pressure in a lot of cases, I am off of meds since surgery...It does put the diabetes in remission, I know that I will always be diabetic but with the help of my sleeve and me watching my food intake it can stay in good control...very happy about that.

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3 minutes ago, Wanda247 said:

Thanks for sharing that and yes it didn't go into a lot of detail but it's true about diabetes and high blood pressure in a lot of cases, I am off of meds since surgery...It does put the diabetes in remission, I know that I will always be diabetic but with the help of my sleeve and me watching my food intake it can stay in good control...very happy about that.

Very awesome! I'm glad to hear that your health had been affected in a positive way so quickly! Metabolic and thyroid disorders are complex. The longer the damage persists, the longer it takes to heal. Hopefully with time, you'll see some positive change in your thyroid function. Keep us posted! 💓

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7 minutes ago, Wanda247 said:

Thanks for sharing that and yes it didn't go into a lot of detail but it's true about diabetes and high blood pressure in a lot of cases, I am off of meds since surgery...It does put the diabetes in remission, I know that I will always be diabetic but with the help of my sleeve and me watching my food intake it can stay in good control...very happy about that.

Very awesome! I'm glad to hear that your health had been affected in a positive way so quickly! Metabolic and thyroid disorders are complex. The longer the damage persists, the longer it takes to heal. Hopefully with time, you'll see some positive change in your thyroid function. Keep us posted! 💓

I found the official study that article was based on https://www.cell.com/cell-reports/fulltext/S2211-1247(13)00125-3

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@Wanda247 the article would not apply to you or I in regards to metabolism changes since we are sleeve patients. The article is talking about changes to bypass patients because of the alteration in the GI tract. Thanks for sharing the article @Kimmie K, it is a good read.

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28 minutes ago, nenes78 said:

@Wanda247 the article would not apply to you or I in regards to metabolism changes since we are sleeve patients. The article is talking about changes to bypass patients because of the alteration in the GI tract. Thanks for sharing the article @Kimmie K, it is a good read.

Thanks for clarifying 👍

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If you want to be totally bored out of your mind, there's a TON of NIH studies explaining how gastric bypass "resets" your metabolism to match your new weight. Here's a boring, technical article that explains why this is only applicable for bypass patients: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158101/ and here is a layman's terms article: http://www.thedoctorwillseeyounow.com/content/diabetes/art4005.html There was a really good article about it I found pre-op... but I can't seem to find it anymore.

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10 minutes ago, Bluesheeler said:

That's the exact same article I pasted earlier, teehee :P

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39 minutes ago, mousecat88 said:

If you want to be totally bored out of your mind, there's a TON of NIH studies explaining how gastric bypass "resets" your metabolism to match your new weight. Here's a boring, technical article that explains why this is only applicable for bypass patients: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158101/ and here is a layman's terms article: http://www.thedoctorwillseeyounow.com/content/diabetes/art4005.html There was a really good article about it I found pre-op... but I can't seem to find it anymore.

I LOVE reading NIH and PubMed studies! LOLOL Your 2nd link is the one I pasted earlier :P Thanks for the other one though. Reading time!

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