Aleve & Advil: DO NOT try this at home!!!!

[DrRX - Tulsa 0]

NSAIDs, even if they are liquid or injections can still cause ulcers, so you still have to be careful. They block COX, (this relieves the pain) COX also protects your stomach from stomach acid.

[Gibson 7]

Oh darlin', believe me...I sat on my ass a LOT. Every once in a while I had to get up to get on the toilet, y'know? Can somebody please tell me why they make those things so low to the ground???? :tired:tired

=) I have no idea. But, I figure between getting up and down from the couch and peeing a dozen times today I'm getting my squats in one way or the other. =)

[faithmd 14]

Okay folks, time for a brief lesson about what NSAID's are:

Nonsteroidal anti-inflammatory drugs (NSAIDs) have the following properties:

analgesic (pain-killing) properties

anti-inflammatory properties

antipyretic (fever-reducing) properties

There are three types of NSAIDs:

salicylates (both acetylated, such as aspirin, and nonacetylated such as salsalate, choline magnesium trisalicylate and magnesium salicylate)

Traditional NSAIDs which include:

Ansaid (Flurbiprofen)

Arthrotec (Diclofenac/Misoprostol)

Cataflam (Diclofenac Potassium)

Clinoril (Sulindac)

Daypro (Oxaprozin)

Dolobid (Diflunisal)

Feldene (Piroxicam)

Ibuprofen (Motrin, Advil)

Indocin (Indomethacin)

Ketoprofen (Orudis)

Lodine (Etodolac)

Meclomen (Meclofenamate)

Mobic (Meloxicam)

Nalfon (Fenoprofen)

Naproxen (Naprosyn, Aleve)

Ponstel (Mefanamic Acid)

Relafen (Nabumetone)

Tolectin (Tolmetin)

Voltaren (Dicolfenac Sodium)

COX-2 selective inhibitors which include:

Celebrex (Celecoxib)

Vioxx (Rofecoxib)(No longer on market as of September 2004)

Bextra (Valdecoxib)(No longer on market as of April 2005)

There are also other COX-2 Inhibitors being developed, including:

Prexige (Lumiracoxib)

Arcoxia (Etoricoxib)

The Enzyme Cyclooxygenase

Further research of the enzyme cyclooxygenase, also known as COX, has revealed that there are two forms, known as COX-1 and COX-2. NSAIDs affect both forms of cyclooxygenase. COX-1 is involved in maintaining healthy tissue, while COX-2 is involved in the inflammation pathway. COX-2 selective inhibitors became the newest subset of NSAIDs born of this research.

Other Facts About NSAIDs

Pain and inflammation sometimes occur in a circadian rhythm (daily rhythmic cycle based on a 24 hour interval). Therefore NSAIDs may be more effective at certain times.

NSAIDs can be divided into two groups: those with plasma (blood) half-lives less than 6 hours (i.e. aspirin, diclofenac, ibuprofen) and those with half-lives greater than 10 hours (i.e. diflunisal, piroxicam, and sulindac). Since it takes three to five half-lives to stabilize blood levels, NSAIDs with longer half-lives require a loading dose to be given (large dose given initially). The "half-life" is the time it takes a drug to go down to half of its initial level.

Prostaglandins, which are inhibited by NSAIDs, function in the body to protect the stomach lining, promote clotting of the blood, regulate salt and Fluid balance, and maintain blood flow to the kidneys when kidney function is reduced. By decreasing prostaglandins, NSAIDs can cause stomach irritation, bleeding, Fluid retention, and decreased kidney function.

Hope this helps!

[cyndilou29 0]

NSAID = non steroidal anti inflammatory drug. IE Ibuprofin (Motrin), Aleve, etc

[dmtjet 0]

It seems soooo hard to know what will cause problems and what won't. I hadn't heard any of this before, so it is an eye opener! Tylenol only for me! Can that be taken whole and what about time release capsules?

[TerriDoodle 6]

There's people who use NSAID's daily (like for arthritis) and those who used them for occasional aches and pains. I'm in the second category. Surely I'm not at risk for ulcers if I take children's liquid Motrin for a day or two once or twice a month, right? Before banding I took Advil for all kinds of things... even if I just didn't "feel good". I've also taken it for acute back pain over a period of several days at max dosages....only then did I start to feel the gastric effects. I wouldn't do that now, after banding, but in "emergencies" like not being able to walk or get up and down from the potty!? I feel like I should be ok.

[TerriDoodle 6]

It seems soooo hard to know what will cause problems and what won't. I hadn't heard any of this before, so it is an eye opener! Tylenol only for me! Can that be taken whole and what about time release capsules?

Tylenol comes in all sorts of usable forms...even melt-in-your-mouth strips and adult liquid formula. I wouldn't risk a capsule getting stuck, but that's me. My doc says if it can't get thru a straw, don't take it and used the example of nothing bigger than a birth control pill.

[Carlene 12]

Tylenol comes in all sorts of usable forms...even melt-in-your-mouth strips and adult liquid formula. I wouldn't risk a capsule getting stuck, but that's me. My doc says if it can't get thru a straw, don't take it and used the example of nothing bigger than a birth control pill.

Tylenol liquid for adults works really quickly. The Go Tabs are convenient, especially if there is nothing available to wash them down with.

[WASaBubbleButt 41]

There's people who use NSAID's daily (like for arthritis) and those who used them for occasional aches and pains. I'm in the second category. Surely I'm not at risk for ulcers if I take children's liquid Motrin for a day or two once or twice a month, right? Before banding I took Advil for all kinds of things... even if I just didn't "feel good". I've also taken it for acute back pain over a period of several days at max dosages....only then did I start to feel the gastric effects. I wouldn't do that now, after banding, but in "emergencies" like not being able to walk or get up and down from the potty!? I feel like I should be ok.

The big issue for banded folks vs. non banded folks is that the bariatric surgeons (for the most part) don't want the NSAID dissolving in your pouch. As another poster pointed out, regardless of route (injectable, oral, SL) NSAIDs can cause stomach trouble but for we banded folks the key is to not let the drug dissolve in your pouch. That is "our" issue due to being banded vs. those that are not banded.

There are some people that are more likely to have additional stomach problems. Someone who already has an ulcer isn't likely to want to take NSAIDs. Someone who is extra sensitive to drugs/stomach issues isn't likely to want to take this class of drug.

If I use injectable Toradol I have no problems whatsoever but if I take the tablet or SL version I have serious problems. It's all because it messes with my pouch. Yet injectable versions give me no problem so I keep injectable Toradol on hand. Others might respond differently and maybe they couldn't even tolerate injectable versions.

Each person is different and unique.

[Serena 0]

My program materials say that Celebrex should only be taken if absolutely necessary and under close medical supervision. The surgeon, a casual, easy-going guy, said no problem --if it helps, take it. I am still concerned but can barely leave the house without it.

Arthritis is the "family curse", and I am the only overweight person in the family. I have major problems even in non-weight bearing joints so weight loss isn't going to make a substantial difference according to the orthopod. Therefore Celebrex and I are doomed to be life-long companions--or at least until something better comes along.

For you young bandsters out there: Celebrex is a prescription NSAID that had the potential to be a little easier on the stomach. It is used mainly for arthritis.

[WASaBubbleButt 41]

My program materials say that Celebrex should only be taken if absolutely necessary and under close medical supervision. The surgeon, a casual, easy-going guy, said no problem --if it helps, take it. I am still concerned but can barely leave the house without it.

Arthritis is the "family curse", and I am the only overweight person in the family. I have major problems even in non-weight bearing joints so weight loss isn't going to make a substantial difference according to the orthopod. Therefore Celebrex and I are doomed to be life-long companions--or at least until something better comes along.

For you young bandsters out there: Celebrex is a prescription NSAID that had the potential to be a little easier on the stomach. It is used mainly for arthritis.

I don't think there is really any way to know if you will have problems until you try it. I had no problems with Toradol before banding, now it's a big problem unless I use the injectable version. I wish I had a better answer for you.

[TerriDoodle 6]

WAS - I wonder if my doc would give me injectible Toradol just to have on hand for aches & pains? Prolly not, eh?

[WASaBubbleButt 41]

WAS - I wonder if my doc would give me injectible Toradol just to have on hand for aches & pains? Prolly not, eh?

I didn't even bother asking mine because I knew he would likely not do it. I bought a bunch in Mexico.

My GP just knows "no NSAIDs" and I'm thinking he doesn't really understand why. Most don't.

If he prescribes something that is a teeny tiny tablet that I can swallow he still won't write it for tablets, only liquids. He's a "by the book" kinda guy. I have a GP in Nogales, Mexico that does understand why we have the issues that we do and he supports my Toradol choices. Although in Mexico you don't need a prescription so it wouldn't matter if he does or does not support the idea.

[Brewa2000 1]

Good discussion!

I have Ankylosing Spondilitis (type of RA). This was the major reason for being banded. I wanted to take some weight off my joints. I used to take Aleve before being banded. My doc now has me take Prevacid then Celebrex. The thinking being the Prevacid would protect my stomach. So far it's working fairly well. Some days are still a bear, especially early morning and evenings. The two meds cost me $70 a month with insurance picking up the rest.

Bruce

[wagnerd 0]

I take tramadol (ultram) for my fibromyalgia and it works great. its not an NSAID