4them 0 Posted November 4, 2010 My doctor told me I had to take this medication called Actigall starting 3 months post op and I would take it for 6 months twice a day. The purpose apparently is to keep you from developing gallstones which can result from rapid weight loss. So I compliantly took the medication only to start suffering severe joint and muscle pain. I called my PCP who said this is a MAJOR side effect and to stop the medication immediately. Apparently this side effect is the medication not being absorbed through the liver like it should be and is being absorbed into the muscle/tissue which can cause permanent muscle damage. Now, if anyone has followed any of my other posts you know I have had NOTHING but bad luck and issue after issue. When this happened I actually started to laugh because it would just figure I would suffer a major side effect from medication that is supposed to help you. Just wondering if anyone else was instructed to take this medication. Obviously, I am no longer taking it. I would rather take my chances of developing gall stones...which at this point....would not be far fetched given everything else I have had happen! Share this post Link to post Share on other sites