I got my first fill last Thursday, 07/01/10. It doesnt hurt at all. They put me on the table, laid me back. He felt for the port then swabbed & cleaned the area with hibiclens. He gave me a shot numb the area then inserted the needle for the fill. He let the nurse know the measurements for where my port was located, then filled it with how ever many cc's. He then had me sit up (with the needle still inserted, didnt hurt at all) and had em drink some water to ensure it went down with ease, it did. That was it. He pulled out the needle and put a bandaid on. The pain is less than getting a blood test, that simple. The whole thing probably took 3 minutes total from prep to finish. So, nothing to worry about.