I wanted to put my 2 cents worth in on this topic because I have been there, and YES, hormones, stress and "inflammation" do affect the tightness (or not) of the band. I learned this a very hard way 6 months ago when I was diagnosed with breast cancer. I was 6 months banded and very successful in my weight loss journey before the "derailment diagnosis" and subsequent surgeries and radiation. A few days after my second surgery my husband and I were having dinner -- very tender filet mignon, brocolli florettes and baked potatoes (potatoes were for him). After 2 bites of the filet and one of the brocolli I felt the pain start -- never had experienced a PB before that, but had read about it here. 20 minutes later the food came back up and I thought I'd feel better, but the pressure and pain never went away. I tried some hot tea about an hour later. Nope. I went to bed thinking I needed to rest, not think about it and start over in the morning. I brushed my teeth in the morning and swallowed a sip of Water and thought "uh oh, this may be worse than I thought" but decided to take my morning medication - a small capsule. It came right back up. I called the surgeon's office and learned he was in surgery but if I came into the clinic where he would be in the afternoon they could see me.
I did not have even a sip of water in me for more than 20 hours by the time I was seen. I was dehydrated and not feeling very well. About 1 cc was removed from my band and I drank a cup of water which felt good, finally!
So the doctor told me that after my surgery I was experiencing an inflammatory response (normal after any kind of surgery) but it had also affected my stoma/band. Inflammation in the body anywhere (like in the joints, or an injured muscle) can affect another area where there is some "compromise" like with a LapBand.
Because of my cancer and upcoming radiation treatment he told me I needed to concentrate on nutrition and adding calories to help fight the disease, which I did. I maintained my weight during the next 4 months -- didn't lose anything, but didn't gain either. I got a .3cc fill after the 2nd month and another .5 the 3rd month and didn't experience any problems. However, the tightness and feeling of too much restriction started about 6 weeks ago, and about the same time I injured my back. My primary care physicion put me on an anti-inflammatary, temporarily, and the result was that I could also eat without PBs or pain, but I also gained a couple pounds!
I saw my surgeon this past week and he added 1cc and encouraged me to continue with the anti-inflammatory medication for a while longer and I think it's a cure! And I have lost the extra pounds I had gained!
So in answer to the question of whether or not there is anything you can take to relieve the yo-yo tightness/looseness, I think an anti-inflammatory is something to ask your doctor about. Aleve, Ibuprofin, and other OTC brands might be enough. I take the generic form of Voltaren which is working for me, but everyone is different.