I was banded in May 08 and began taking Zoloft (50 mg) in Dec. Within 5 minutes of taking it the fire began and I spent some time vomiting and sliming. A few more doses and I realized the extreme reflux must be from the pill. I've tried taking it with a protein drink but still experience the firey pain. I specifically came looking at the threads here to see if anyone else experiences the problem. I will try taking it with yogurt and see what happens.