Relief is usually given by either massaging or stretching the foot, ankle or knee in the opposite direction of the spasm.
Colloquial advice suggests that dietary deficiency of potassium, found richly in bananas and many vegetables,is a common cause of these spasms. It can be Calcium, magnesium or potassium but majority of people lack potassium when sedentary or lack of movement or after a surgery. This is what Wikipedia had for a solution. It's still best to give your Dr. a call, too.
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