It's notorious to cause metabolic syndrome.
I have been on 150 mg of Seroquel for four years to treat my disassociation due to PTSD. It saved my life and was a game changer in my mental health. It contributed to a 100lb weight gain in one year. I can eat vegan, fast food, paleo, Atkins, you name it, and my weight won't budge from 247lbs. I am scheduled to have my sleeve in February and I am petrified that I may have to go off the medicine.