I went from 1 or 2 migraines a year to about 9 a month. After a year or so of this my doctor had me try Topamax. I've been on 25 mg Topamax., once a day, for the past three weeks and I'm very happy with it. I've only had the beginnings of 3 migraines (immediately took my Relpax) and they went immediately away. I feel like I've got my life back. My only side effects are a slight loss of appetite (which I'm not unhappy about) and a little tingling in my feet. Well worth it.