Y'know I have been wondering the same thing myself. I love to sew, have my degree in design but have sworn off clothes because of my size. I have cast on for a sweater though in a medium since they take me a while to complete.
I plan to sew t shirts in several sizes to get my through my initial weight loss. I have a stack of jeans from the way up. Not sure I would start on a fully hand padded jacket though.