I am almost 3 years post-op and just recently starting having problems with taking my Zoloft. At first I thought the pill was too large so I split it in half, which seemed to work. However I've now started having severe reflux pain immediately after taking the pill. A doctor sent me for an upper GI where they found a hiatel hernia, but this shouldn't be causing the pain. I am being told now to get scoped. I found a thread on the lap band forum where several patients from that surgery are experiencing the pain as well, but the cause they identified (bacteria from the colon coming up through their stomach to the pouch) wouldn't explain this for gastric bypass patients. I'm curiuous to see how many RNY patients taking zoloft have this problem and what they have been able to do to fix it. Thanks!