I've been on small planes on short hops where about the time you reach "altitude" you start preparing for desent. I've been on big planes on 14 hour flights. I prefer the larger planes but only because I got used, on those long hauls, to standing up most of the flight, and there is no place to stand in the small planes. (And no time to stand on short hops.)
I like take-off, and about the only time I sleep on a plane is during landing. I like the minor pressure of take-off, and there is something about landing that is very soothing to me.
Switching planes should not be too difficult, but it depends on the airport. Most likely if you are not going abroad, you won't have far to go between your arrival and departure gates. There are boards with all arrivals and departures listed, their planned arrival/departure times, any delays, and the gate all displayed in a table. If you don't see one, ask, and if you are not sure which direction to your gate, ask again. But Amanda Rae has made a very good suggestion. You can try that. If your layover is short, that would be your best bet.
They do hold planes for delayed flights with connecting passengers. I've sat in many cabins waiting for delayed connections. And many airlines will have someone at your arrival gate who can tell you where your connection is. They will also usually announce all connections during landing.
The worse part of the flight for me is loading an unloading. In some countries, people stand up as soon as the plane stops, and it seems like it takes 15 minutes or more before they even open the doors. Then it is another 10 minutes or so while people in the aisles get their carry-ons out of the overheads. I just sit in my seat until the aisles are clear.