My husband takes uloric &collects both daily for gout finally a arthritis specialist put him on these meds together, his kidneys are@ 60 percent functioning . This is after removal of big toe &'re attachment & now able to get his protein in w/barracks of gout, talk to it dr about this medicine we went to Vanderbilt university in Nashville for best dr . He now eats normal amounts of protein &even Protein shakes.