I'm 2 days post op and took my daily pills this morning. One is small, so I wasn't worried about that one. The other one is a little bigger (It is a 100mg Pristiq XR), it can't be cut because it is extended release. Its about a 1/2 inch square. I took it about an hour ago and it feels like I've got a huge rock right behind my sternum. I've been following the post-op clear liquid diet religiously and haven't felt anything like this! It's horrible! I'm afraid it's stuck. Will it go down eventually? I thought that things didn't usually get stuck for long periods of time... They either went down or came up. Do I need to contact my Dr's office?